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FORMULATION, EVALUATION AND OPTIMIZATION OF NASAL MUCOADHESIVE IN SITU GEL OF STIRIPENTOL USING IN-VITRO, EX-VIVO AND IN-VIVO METHODS

    2 Author(s):  WANI RAKESH M , SINGH ANOOP

Vol -  11, Issue- 1 ,         Page(s) : 20 - 36  (2024 ) DOI : https://doi.org/10.32804/IRJMSI

Abstract

The objective of the present research work was to develop and evaluate the nasal in situ gel formulations of Stiripentol for better availability in the brain. Mucoadhesive in-situ gelling Stiripentol formulation were successfully prepared by the spontaneous emulsification method (titration method) using Capmul MCM as the oil

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2. Hoffman A, Stepensky D, Lavy E, Eyal S, Michael F. Review of expandable gastro retentive dosage forms. J Control Release 2003; 90:143-62.

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